Effect of guar gum supplementation on lipidic and glycidic metabolic control and body mass index in type 2 diabetes
Palabras clave:
body mass index, diabetics mellitus Type 2, guar gum, metabolic controlResumen
Objective
To evaluate the effects of guar gum supplementation in the metabolic control and body mass index (BMI) of
type 2 diabetic patients.
Methods
A total of 17 (12 women and 5 men) participants ingested 10 grams of fiber supplement daily for three
months. Changes in BMI and the biochemical parameters (fasting glycemia, glycosilated hemoglobin (HbA1c),
total plasma cholesterol and triglycerides) were evaluated at the beginning and the end of the study.
Results
No changes in mean BMI (p=0.770), mean fasting glycemia (p=0.09) or triglyceride levels were observed.
However, significant increases in HbA1c levels were observed (p<0.001) following the ingestion of guar gum
supplements. Posterior analysis indicated that the five participants that had the highest mean fasting blood
glucose and HbA1c levels, showed a significant reduction in their fasting glycemic levels (p=0.03) at the end of
the study. A significant (p<0.001) reduction in total cholesterol levels was observed after three months of guar
gum supplementation.
Conclusion
Guar gum supplementation (10g/day) in the diet of overweight type 2 diabetics, resulting in total fiber
ingestion close to 20g per day, did not lead to a spontaneous reduction in body weight. The effect of guar
gum on the glycidic metabolic control was inconclusive, but it was shown to be an effective dietetic strategy to
reduce blood cholesterol levels.
Citas
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Derechos de autor 2023 Mirela dos Santos Ourique FIGUEIREDO, Rita de Cássia Gonçalves ALFENAS, Sylvia do Carmo Castro FRANCESCHINI, Maria do Carmo Gouveia PELUZIO, Raquel Monteiro AZEREDO, Sônia Machado Rocha RIBEIRO
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
