O desmame precoce afeta o ganho de peso e a composição corporal em camundongos adultos?
Palavras-chave:
Aleitamento materno, Camundongos, Composição corporal, Consumo alimentar, Desmame precoceResumo
Objetivo
Avaliar o efeito do desmame precoce sobre o ganho de peso e a composição corporal de camundongos adultos jovens.
Métodos
Camundongos Swiss Webster, machos, foram desmamados precocemente (14º dia de vida) ou amamentados até o 21º dia de vida (grupo controle). Após o desmame, os animais foram alimentados com ração elaborada para roedores em crescimento até o 63º dia de vida, quando então foram sacrificados.
Resultados
O peso corporal dos animais do grupo desmamado de forma precoce foi significantemente maior no 28º, 35º e no 63º dias de vida em relação ao grupo controle (p<0,05). Porém, o consumo de ração não diferiu entre os grupos. A concentração sérica de proteínas totais, albumina e ferro, bem como a concentração hepática, muscular e cerebral de proteínas, ácido desoxirribonucléico e a relação proteína/ácido ribonucléico, não diferiram significantemente entre os grupos. O grupo desmamado precocemente apresentou maior quantidade absoluta de massa magra, lipídeos, proteínas e cinzas, em comparação ao grupo controle (p<0,05). A quantidade relativa de umidade, lipídeos, massa magra, proteínas e cinzas não diferiu entre os grupos.
Conclusão
O desmame precoce, associado à ingestão de ração elaborada para roedores em crescimento, resultou em aumento do ganho de peso, porém não afetou a composição corporal de camundongos adultos.
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Copyright (c) 2023 Marcelo Macedo ROGERO, Maria Carolina BORGES, Ivanir Santana de Oliveira PIRES, Julio TIRAPEGUI
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