Atualização das apresentações clínicas que cursam com ageusia e disgeusia
uma revisão bibliográfica
DOI:
https://doi.org/10.24220/2318-0897v32a2023e5827Palabras clave:
Ageusia, Disgeusia, Distúrbios do PaladarResumen
Compreender as alterações gustativas é relevante para identificação de outras doenças ou agravos à saúde quando excluídos a infecção por SARS-CoV-2 e o tratamento antineoplásico. Assim, é necessário que os profissionais de saúde saibam reconhecer doenças queestão associadas às alterações de paladar, quando descartada a infecção em razão do coronavírus. Foram realizadas buscas nas bases de dados PubMed, MedLine e SciELO, através dos descritores: “Ageusia” e “Disgeusia”, limitando o período de busca entre os anos de 2017 a 2021. Foram incluídos artigos originais, no idioma inglês. Os dados obtidos foram submetidos a uma análise quantitativa simples, selecionando os resumos pertinentes a essa revisão. Foram excluídos artigos que relacionaram tais alterações de paladar ao coronavírus e ao tratamento antineoplásico. Foram selecionados seis estudos, dos 61 encontrados, que em conjunto analisaram uma amostra total de 573 indivíduos. O sabor metálico foi a alteração de paladar relatada com maior frequência, já o sabor doce foi o mais facilmente detectado pelos indivíduos testados, havendo maior facilidade de percepção entre a população feminina. A maioria dos indivíduos relata que a frequência com que este sintoma se apresenta é diária, mas a duração de persistência do sintoma não é descrita. É necessário compreender as alterações de paladar no contexto de outras doenças, quando excluída o coronavírus.
Descargas
Citas
Rathee M, Jain P. Ageusia. Encyclopedia of the Neurological Sciences 2021[citado 2022 Maio 23];69-71. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK549775/
Lopes ACF, Pereira CSS, Fernandes FL, Valente LC, Valadão AF, Abreu MNS et al. Prevalência de alterações gustativas em idosos em uso crônico de fármacos. Geriatrics Gerontology Aging. 2015;9(2):132-7. https://doi.org/10.5327/z2447-2115201500040002 DOI: https://doi.org/10.5327/Z2447-2115201500040002
Rodrigues D, Gomes P, Schirmer CL, Oliveira Â, Nolte A, Gonçalves Bós ÂJ et al. Avaliação do paladar de idosos e sua relação com estado nutricional e hábitos alimentares. PAJAR. 2020;8(1):e37707. https://doi.org/10.15448/2357-9641.2020.1.37707 DOI: https://doi.org/10.15448/2357-9641.2020.1.37707
Taruno A, Nomura K, Kusakizako T, Ma Z, Nureki O, Foskett JK. Taste transduction and channel synapses in taste buds. Pflugers Archiv Eur J Phys. 2021;473(1):3-13. https://doi.org/10.1007/s00424-020-02464-4 DOI: https://doi.org/10.1007/s00424-020-02464-4
Palheta Neto FX, Targino MN, Peixoto VS, Alcântara FB, Jesus CC, Araújo DC et al. Anormalidades sensoriais: olfato e paladar. Arq Inter Otorrinol. 2011;15(3):350-8. https://doi.org/10.1590/S1809- 48722011000300014 DOI: https://doi.org/10.1590/S1809-48722011000300014
Costa KVT, Carnaúba ATL, Rocha KW, Andrade KCL, Ferreira SMS, Menezes PL. Olfactory and taste disorders in COVID-19: a systematic review. Bra J Otorhinol. 2020;86(6):781-92. https://doi.org/10.1016/j.bjorl.2020.05.008 DOI: https://doi.org/10.1016/j.bjorl.2020.05.008
Saniasiaya J, Islam MA, Abdullah B. Prevalence and characteristics of taste disorders in cases of COVID-19: a meta-analysis of 29,349 patients. Otolaryngol Head Neck Surg. 2021;165(1):33-42. https://doi.org/10.1177/0194599820981018 DOI: https://doi.org/10.1177/0194599820981018
Jafari A, Alaee A, Ghods K. The etiologies and considerations of dysgeusia: a review of literature. J Oral Biosci. 2021;63(4):319-26. https://doi.org/10.1016/j.job.2021.08.006 DOI: https://doi.org/10.1016/j.job.2021.08.006
Kaufman A, Kim J, Noel C, Dando R. Taste loss with obesity in mice and men. Int J Obes (Lond). 2020;44(3):739-43. https://doi.org/10.1038/s41366-019-0429-6 DOI: https://doi.org/10.1038/s41366-019-0429-6
Prado-Netto A, Marques TG, Prado-Netto G. Aquisição gustativa na infância: teoria e estudos. Rev Saúde Desenvol Humano. 2017;5(2):75-84. https://doi.org/10.18316/sdh.v5i2.3431 DOI: https://doi.org/10.18316/sdh.v5i2.3431
Revathishree K, Shyam Sudhakar S. Ageusia: a symptom of peritonsillar abscess? Indian J Otolaryngol Head Neck Surg. 2021;1. https://doi.org/10.1007/s12070-021-02506-y DOI: https://doi.org/10.1007/s12070-021-02506-y
Tricco A, Lillie E, Zarin W, O’Brien K, Colquhoun H, Levac D et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR) : Checklist and Explanation. Ann of Intern Med. 2018[citado 22 Maio 23; Available from: https://doi.org/10.7326/M18-0850 DOI: https://doi.org/10.7326/M18-0850
Meschenmoser P, Meuschke N, Hotz M, Gipp B. Scraping scientific web repositories: Challenges and solutions for automated content extraction. D-Lib Magazine. 2016;22:9-10. https://doi.org/10.1045/ september2016-meschenmoser DOI: https://doi.org/10.1045/september2016-meschenmoser
Donato H, Donato M. Stages for undertaking a systematic review. Acta Med Port. 2019;32:227-35. DOI: https://doi.org/10.20344/amp.11923
De Carli L, Gambino R, Lubrano C, Rosato R, Bongiovanni D, Lanfranco F, et al. Impaired taste sensation in type 2 diabetic patients without chronic complications: a case-control study. J Endocrinol Invest. 2018;41(7):765-72. https://doi.org/10.1007/s40618-017-0798-4 DOI: https://doi.org/10.1007/s40618-017-0798-4
Šijan Gobeljić M, Milić V, Pejnović N, Damjanov N. Chemosensory dysfunction, Oral disorders and Oral health-related quality of life in patients with primary Sjögren’s syndrome: comparative cross-sectional study. BMC Oral Health. 2020;20(1). https://doi.org/10.1186/s12903-020-01169-5 DOI: https://doi.org/10.1186/s12903-020-01169-5
Singh PB, Young A, Homayouni A, Hove LH, Petrovski BÉ, Herlofson BB et al. Distorted Taste and Impaired Oral Health in Patients with Sicca Complaints. Nutrients. 2019;11(2). https://doi.org/10.3390/nu11020264 DOI: https://doi.org/10.3390/nu11020264
Sødal ATT, Singh PB, Skudutyte-Rysstad R, Diep MT, Hove LH. Smell, taste and trigeminal disorders in a 65-year-old population. BMC Geriatr. 2021;21(1):1-12. https://doi.org/10.1186/s12877-021-02242-6 DOI: https://doi.org/10.1186/s12877-021-02242-6
Barragán R, Coltell O, Portolés O, Asensio EM, Sorlí J v., Ortega-Azorín C, et al. Bitter, sweet, salty, sour and umami taste perception decreases with age: Sex-specific analysis, modulation by genetic variants and taste-preference associations in 18 to 80 year-old subjects. Nutrients. 2018;10(10). DOI: https://doi.org/10.3390/nu10101539
Alia S, Aquilanti L, Pugnaloni S, Di Paolo A, Rappelli G, Vignini A. The influence of age and oral health on taste perception in older adults: A case-control study. Nutrients. 2021;13(11). DOI: https://doi.org/10.3390/nu13114166
Ros C, Alobid I, Centellas S, Balasch J, Mullol J, Castelo-Branco C. Loss of smell but not taste in adult women with Turner’s syndrome and other congenital hypogonadisms. Maturitas. 2012;73(3):244-50. https://doi. org/10.1016/j.maturitas.2012.07.012 DOI: https://doi.org/10.1016/j.maturitas.2012.07.012
Dahir NS, Calder AN, McKinley BJ, Liu Y, Gilbertson TA. Sex differences in fat taste responsiveness are modulated by estradiol. Am J Physiol Endocrinol Metabol. 2021;320(3):E566. https://doi.org/10.1152/ajpendo.00331.2020 DOI: https://doi.org/10.1152/ajpendo.00331.2020
Dawes C, Pedersen AML, Villa A, Ekström J, Proctor GB, Vissink A, et al. The functions of human saliva: a review sponsored by the World Workshop on Oral Medicine VI. Arch Oral Biol. 2015;60(6):863-74. https://doi.org/10.1016/j.archoralbio.2015.03.004 DOI: https://doi.org/10.1016/j.archoralbio.2015.03.004
Lim SXL, Höchenberger R, Busch NA, Bergmann M, Ohla K. Associations between Taste and Smell Sensitivity, Preference and Quality of Life in Healthy Aging-The NutriAct Family Study Examinations (NFSE) Cohort. Nutrients. 2022;14(6):1141. https://doi.org/10.3390/nu14061141. DOI: https://doi.org/10.3390/nu14061141
Dellafiore F, Bascape B, Baroni I, Caruso R, Conte G, Udugampolage NS et al. What is the relations between dysgeusia and alterations of the nutritional status? A metanarrative analysis of integrative review. Acta Biomed. 2021;92(S2). https://doi.org/10.23750/abm.v92iS2.11015
Tepper BJ, Barbarossa IT. Taste, Nutrition, and Health. Nutrients. 2020;12(1):155. https://doi.org/10.3390/nu12010155 DOI: https://doi.org/10.3390/nu12010155
Berube L, Duffy VB, Hayes JE, Hoffman HJ, Rawal S. Associations between chronic cigarette smoking and taste function: Results from the 2013–2014 national health and nutrition examination survey. Physiol Behav. 2021;240:113554. https://doi.org/10.1016/j.physbeh.2021.113554 DOI: https://doi.org/10.1016/j.physbeh.2021.113554
Kale YS, Vibhute N, Belgaumi U, Kadashetti V, Bommanavar S, Kamate W. Effect of using tobacco on taste perception. J Family Med Prim Care. 2019;8(8):2699. https://doi.org/10.4103/jfmpc.jfmpc_457_19 DOI: https://doi.org/10.4103/jfmpc.jfmpc_457_19
Kinugasa Y, Nakayama N, Sugihara S, Mizuta E, Nakamura K, Kamitani H et al. Polypharmacy and taste disorders in heart failure patients. Eur J Prev Cardiol. 2020;27(1):110-1. https://doi. org/10.1177/2047487319856717 DOI: https://doi.org/10.1177/2047487319856717
Jensterle M, Ferjan S, Battelino T, Kovač J, Battelino S, Šuput D et al. Does intervention with GLP-1 receptor agonist semaglutide modulate perception of sweet taste in women with obesity: study protocol of a randomized, single-blinded, placebo-controlled clinical trial. Trials. 2021;22(1). https://doi.org/10.1186/s13063-021-05442-y DOI: https://doi.org/10.1186/s13063-021-05442-y
Kumbargere Nagraj S, George RP, Shetty N, Levenson D, Ferraiolo DM, Shrestha A. Interventions for managing taste disturbances. Cochrane Database Syst Rev. 2017;2017(12). https://doi.org/10.1002/14651858.CD010470.pub3 DOI: https://doi.org/10.1002/14651858.CD010470.pub3
Nomura Y, Toi T, Ikeda M, Ikeda A, Tanaka M, Oshima T. Prognostic factors of recovery with medication in patients with taste disorders. Plos One. 2020;15(10):e0237270. https://doi.org/10.1371/journal.pone.0237270 DOI: https://doi.org/10.1371/journal.pone.0237270
