Polimiosite e síndrome de Klinefelter
uma associação rara
Palabras clave:
polimiosite, sindrome de klinefelter, hipogonadismoResumen
Os papéis facilitadores do estrogênio e protetores do androgênio em relação às desordens auto-imunes já são conhecidos. O estado de hipogonadismo masculino provocado pela Síndrome de Klinefelter pode favorecer o aparecimento de doenças auto-imunes concomitantes como Lúpus Eritematoso Sistêmico, Esclerose Sistêmica, Polimiosite, Artrite Reumatóide e Tireoidite de Hashimoto. Os autores relatam a rara associação entre Síndrome de Klinefelter e miopatia inflamatória crônica caracterizada como Polimiosite.
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ANSAR AHMED, S., TALAL, N. Sex hormone and autoimmune rheumatic disorders. Scand J Rheumatol. Stockholm, v.18, n.2, p.69-76, 1989.
BALESTRAZZI, P. et al. Juvenile rheumatoid arthritis in Turner's syndrome. Clin Exp Rheumatol, Brussels, v.4, n.1, p.61-62, 1986.
GILLILAND, w.R., STASHOWER, M.E. Klinefelter's syndrome and systemic lupus erythematosus. Clin Exp Rheumatol, Pisa, v.18, n.1, p. 107-109, 2000.
KOBAYASHI, S. et al. Klinefelter's syndrome associated with progressive systemic sclerosis: report of a case and review of the literature. Clin Rheumatol, Brussels, v. IO, n.1, p.84-86, 1991.
KOBAYASHI, S. et al. Klinefelter's syndrome and rheumatoid arthritis. Report of a case and review of the literature. Clin Rheumatol, Brussels, v. 13, n.13, p.500-503, 1994.
LAHITA, G.L., BRADLOW, H.L. Klinefelter's syndrome: hormone metabolism in hypogonadal males with systemic lupus erythematosus. J Rheumatol, Toronto, v.14, p.154-157, 1987. Supplement 13.
LAHITA, R.G. Sex hormones and systemic lupus erythematosus. Rheum Dis Clin North Am, Philadelphia, v.26, n.4, p.951-968, 2000.
MEDSGER, T.A., ODDIS, C.V. Inflammatory Muscie Disease. In: KLIPPEL, J.H., DIEPPE, P.A. (Ed.). Rheumatolou. 2.ed. New York: Mosby, 1998. Section 7, p.13.1-13.14.
MIYAGAWA, S. et al Systemic lupus erythematosus and anticardiolipin antibodies in Klinefelter's syndrome. Lupus, Houndmills, v.4, n.3, p.236-238, 1995.
MURAKAMI, M. et al. The first report of Klinefelter's syndrome associated with polymyositis. J Jap Soc Inter Med, v.77, p.60-65, 1998.
SANTER, R.J. Male hypogonadism. In: FELEG, P., BAXTER, J.D., FROHMAN, L.A. (Ed.). Endocrinologv and metabolism. 3.ed. [s.l. : s.n.], 1995. cap. 16, p.928-931.
TAKEUCHI, Y. et al. Klinefelter's syndrome accompanied by mixed connective tissue disease and diabetes mellitus. Intern Med, v.38, n.1 1, p.838-839, 1999.
