ANTHROPOMETRIC ANO BIOCHEMICAL ASPECTS, SIGNALS ANO SYMPTOMS IN FEMALE PATIENTS WITH PULMONARY TUBERCULOSIS

Authors

  • Carla Ribeiro Nogueira
  • Gabriela Villaça Chaves
  • Michelle Teixeira Teixeira
  • Carlos Antônio da Silva Franc
  • Andréa Ramalho

Keywords:

nutrition assessment, protein-energy malnutrition, tuberculosis, pulmonary

Abstract

Objective

The purpose of the study is to correlate the protein-energy malnutrition in female patients with the presence of pulmonary tuberculosis, through the evaluation of anthropometric and biochemical data, and clinica/ findings.

Methods

Thirty-one female patients were admitted into hospital, presenting pulmonary tuberculosis diagnosis, confirmed by the Instituto Estadual de Doenças do Tórax Ary Parreiras, in Rio de Janeiro. They had their body mass index, muscular circumference of the arm, and total lymphocyte counting in the peripheral blood, evaluated. The main signals and symptoms re/ated to the pulmonary tuberculosis were registered at the moment of admission into the hospital.

Results

Out of the 37 patients, 67.3% presented protein-energy malnutrition and 71% showed depletion of fat-free mass, evaluated through muscular circumference. There were statistically significant correlations of the body mass index with the total lymphocyte counting (p=0.007), and with the muscular circumference of the arm (p<0.0001), and between the muscular circumference of the arm and the total lymphocyte counting (p=O.005). There was a statistical/y significant difference (p<0.05) in the presence of dyspnea, hemoptysis and hiporexia when conditions of the nourished and the malnourished patients were compared.

Conclusion

This study suggests a strong correlation between the pulmonary tuberculosis and protein-energy malnutrition. The hiporexia and hemoptysis were co-factors,

while the protein-energy malnutrition disease had been worsened due to the decrease in food intake. These findings show the need for a careful alimentary program for such patients, in arder to improve their clinica/ prospective, thus curtailing the protein-energy malnutrition and improving the survival rates

Downloads

Download data is not yet available.

References

World Health Organization. Practical guidelines for tuberculosis contrai. World Health Organization, the lnternational Union against Tuberculosis and Lung Disease, and the Centers for Disease Contrai, USA. Nurs RSA. 1993; 8(8):23,26-8.

Brasil. Ministério da Saúde. Tuberculose: guia de vigilância epidemiológica/elaborado pelo Comitê Técnico-Científico de Assessoramento à Tuberculose e Comitê Assessor para Co-infecção HIV-Tuberculose. Brasília Fundação Nacional de Saúde; 2002.

Brasil. Ministério da Saúde. Sistema Nacional de Agravos de Notificação (SINAN). Taxa de incidência de tuberculose por todas as formas. Brasília: Secretaria da Saúde. Departamento de Informação e Comunicação em Saúde; 2001.

Brasil. Ministério da Saúde. Plano Nacional de Controle da Tuberculose. Brasília: Fundação Nacional de Saúde; 1999.

Rieder HL. Epidemilogic basis of tuberculosis contrai. Paris: lnternational Union against Tuberculosis and Lung Disease; 1999.

World Health Organization. Gender and tuberculosis. ln Global Tuberculosis Contrai. Geneva: WHO; 2003.

Tindó H, Cesar Cavalcante S, Werneck-Barroso E. Gender differences in tuberculosis in Rio de Janeiro, Brazil. lnt J Tuberc Lung Dis. 2004; 8(3):388-90.

Natalizi DA. Associação entre deficiência de vitamina A e tuberculose pulmonar grave [dissertação]. Rio de Janeiro: Universidade Estadual do Rio de Janeiro; 2003.

Silva GA. Da influência dos climas sobre o desenvolvimento da tísica pulmonar: quais as condições higiênicas mais favoráveis ao tratamento desta moléstia? [tese]. Rio de Janeiro: Faculdade de Medicina; 1879.

O. Dias MR. Da tuberculose e o casamento [tese]. Rio de Janeiro: Faculdade de Medicina; 1907.

Ramachandran G, Santha T, Garg R, Baskaran D, lliayas SA, Venkatesan P. et ai. Vitamin A leveis in sputum­ positive pulmonary tuberculosis patients in comparison with household contacts and healthy "normais". lnt J Tuberc Lung Dis. 2004; 8(9):1130-3.

Macallan DC. Malnutrition in tuberculosis. Diagn Microbial lnfect Dis. 1999; 34(2) 153-7.

Schwenk A, Macallan DC. Tuberculosis, malnutrition and wasting. Curr Opin Clin Nutr Metab Care. 2000; 3(4):285-91.

van Lettow M, Kumwenda JJ, Harries AD, Whalen CC, Taha TE, Kumwenda N, et ai. Malnutrition and the severity of lung disease in adults with pulmonary tuberculosis in Malawi. lnt J Tuberc Lung Dis. 2004; 8(2):211-7.

Whalen C, Okwera A, Johnson J, Vjecha M, Horn D, Wallis R, et ai. Predictors of survival in human immunodeficiency virus-infected patients with pulmonary tuberculosis. The Makerere University­-C ase Western Reserve University Research Collaboration. Am J Respir Crit Care Med. 1996; 153(6 Pt 1):1977-81.

Schwander SK, Dietrich M, Mugyenyi P, Kityo C, Okwera A, Johnson J, et ai. Clinicai course of human immunodeficiency virus type 1 associated with pulmonary tuberculosis during short-course antituberculosis therapy. East Afr Med J. 1997; 74(9):543-8.

World Health Organization. Expert Committee Physical status: The use and interpretation of anthropometry. World Health Organ Tech Rep Ser. 1995; 854:1-452.

Frisancho AR. New norms of upper limb fat and muscle areas for assessment of nutritional status. Am J Clin Nutr. 1981; 34(11)2540-5.

World Health Organization. Global tuberculosis contrai. 275 Geneva: WHO; 2000.

Kritski AL, Ruffino-Netto A. Health sector reform in Brazil: impact on tuberculosiscontrai and perspectives. lnt J Tuberc Lung Dis. 2000; 4(7):622-6

Ruffino-Netto A. Tuberculosis: the negleted calamity. Rev Soe Bras Med Trop. 2002; 35(1):51-8.

Santo AH, Pinheiro CE, Jordani MS. Multiple-causes of death related to tuberculosis in the State of Sao Paulo, Brazil, 1998. Rev Saúde Pública. 2003; 37(6):714-21

Ramalho RA, Costa RS, Vieira ACRE, Silva LB, Machado FCP, Menezes SEM, et ai. Avaliação nutricional de pacientes com tuberculose pulmonar atendidos na UISHL Boi Pneumol Sanit. 2000; 8(2):13-20.

Karyadi E, Schultink W, Nelwan RH, Gross R, Amin Z, Dolmans WM, et ai. Poor micronutrient status of active pulmonary tuberculosis patients in lndonesia. J Nutr. 2000; 130(12):2953-8.

Harries AD, Nkhoma WA, Thompson PJ, Nyangulu DS, Wirima JJ. Nutritional status in Malawian patients with pulmonary tuberculosis and response to chemotherapy. Eur J Clin Nutr. 1988; 42(5):445-50.

Zachariah R, Spielmann MP, Harries AD, Salaniponi FM. Moderate to severe malnutrition in patients with tuberculosisis a risk factor associated with early death. Trans R Soe Trop Med Hyg. 2002; 96(3) 291-4

Boelaert JR, Gordeuk VR. Protein energy malnutrition and risk of tuberculosis infection. Lancet. 2002; 5;360(9339):1102.

van Crevel R, Karyadi E, Netea MG, Verhoef H, Nelwan RH, West CE, et ai. Decreased plasma leptin concentrations in tuberculosis patients are associated with wasting and inflammation. J Clin Endocrinol Metab. 2002; 87(2):758-63.

Blackburn GL, Thornton PA. Nutritional assessment of the hospitalized patient. Med Clin North Am. 1979; 63(5): 11103-15.

Pereira CAC. Nutrição em doença pulmonar obstrutiva crônica. Treatment in chronic obstructive pulmonary disease. J Pneumol. 1988; 14(1):45-54.

van Lettow M, van der Meer JW, West CE, van Crevel R, Semba RD. lnterleukin-6 and human immunodeficiency vírus load, but not plasma leptin concentration, predict anorexia and wasting in adults with pulmonary tuberculosis in Malawi. J Clin Endocrinol Metab. 2005; 90(8):4771-6. Epub 2005

May 31.

Macallan DC, McNurlan MA, Kurpad AV, Souza G, Shetty PS, Calder AG, et ai. Whole body protein metabolism in human pulmonary tuberculosis and undernutrition: evidence for anabolic block in tuberculosis. Clin Sei (Lond). 1998; 94(3):321-31.

Published

2006-06-30

How to Cite

Nogueira, C. R., Chaves, G. V., Teixeira, M. T., Franc, C. A. da S., & Ramalho, A. (2006). ANTHROPOMETRIC ANO BIOCHEMICAL ASPECTS, SIGNALS ANO SYMPTOMS IN FEMALE PATIENTS WITH PULMONARY TUBERCULOSIS. Revista De Ciências Médicas, 15(4). Retrieved from https://seer.sis.puc-campinas.edu.br/cienciasmedicas/article/view/1098

Issue

Section

Artigos Originais