Sociodemographic and clinical factors associated with depression in epilepsy
aspectos sociodemográficos e clínicos associados
Keywords:
Depression, Epilepsy, IncidenceAbstract
Objective
This study aimed to evaluate the occurrence of depression and its relationships with sociodemographic and clinical factors in adult patients with focal epilepsy.
Methods
A total of 87 adult patients (age = 44.2 standard deviation=14.8 years) were assessed using medical history, neurological evaluation and Hamilton depression scale. They had symptomatic or probably symptomatic focal epilepsy. The relationships between depression in the Hamilton depression scale and
sociodemographic and clinical aspects were studied. Statistical tests were done with the significance level set at p<0.05.
Results
Fifty-three patients had depression in the Hamilton depression scale (mild in 42 cases, moderate in 8, and severe in 3 cases). Depression was more prevalent in
women and in temporal lobe epilepsy patients with hippocampus sclerosis (regression analysis, p<0.05). There were no significant statistical relationships
among the other clinical variables and the presence of depression.
Conclusion
Depression is common among patients with focal epilepsy and may impact quality of life more than the frequency of seizures. The present study suggests the
existence of sociodemographic and biological factors associated with depression. Good knowledge of these factors can be important for the diagnostic and care
strategies provided to epilepsy patients.
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