MALIGNANTY SKIN TUMORS
SECTIONAL AND ANALYTICAL STUDY OF 83 CASES
Keywords:
neoplasias cutaneas, carcinoma basocelular, carcinome de celulas escamosas, melanomaAbstract
The primary skin cancer is more frequent in Caucasian people, being the malignant melanoma the principal death cause among all the diseases originated from the skin. Eighty-three cases of skin cancer with anatomic-pathological proof have been investigated. Patients were submitted to operative treatment at Plastic Surgery Service of Hospital e Maternidade Celso Pierro, Puc-Campinas from May1996 to May 1997. From the total of patients analyzed, 44 (53.0%) were male, 39 (47.0%) female and 46, 6% of the cases were in the age group above 7() years old. About the histological diagnosis, 65 patients (72.2%) presented basal cell carcinoma, 16 (17.7%) squamous cell carcinoma, 4 (4.3%) melanoma and 5 (5.5%) other neoplasms. Considering the anatomic-pathological diagnosis, the distribution of the skin tumors was analyzed in the variants: sex, age group, type of skin and sunlight exposure, tumor and basal cell carcinoma location in the face and anatomic-pathological confirmation of preoperative diagnosis. It was concluded that the incidence regarding sex, age group, histological type and lesions topography is in accordance with the literature, although the national statistics is undere stimated by data losses.
Downloads
References
ANESSI, G., BALIVA, G. Basal celi and squamous cell carcinomas- clinical histological features. Ann Ist Surg Sanita, Roma, v.32, n.1, p.29-36, 1996.
ARMSTRONG, B. K. The epidemiology and prevention ofcancer in Australia.A ust NZJSurg, Victorw v.58, p. 179-187, 1998.
BONI, R. et al. Concordance of genetic changes in basal cell carcinoma and associated clusters of squamous cells. J Invest Dermatol, New York,
BRASH, D.E. Sunlight and the onset ofskin cancer. Trends Genet,Barking, v. 13, n. 10, p.410-414, 1997.
CALVERT, G.M.et al. Cancer risks among workers exposed to metal working fluids: a systematic review. Am J Ind Med, New York, v.33, n.3, p.282-292, 1998.
ENGLISH, D.R.et al. Incidence ofnon-melanocytic skin cancer in Geraldton, Western Australia.ln J Cancer,New York, v.73, n.5, p.629-633, 1997a.
ENGLISH, D.R. et ai. Suniight and cancer. Cancer Causes Control, Oxford, v.8, n.3, p.271-83, 1997b.
FRIEDAMN, R.J. et al. The continued importance of early detection of malignant melanoma. CA: CancerJC1in, New York, n.41, p.201-226, 1991. 9. GARCIA, G.E. et al. Carcinoma basocelular: evaluación clinico-patologica de 150 casos. An SocMex Oftalmol, v.60, n. 1 , p.20-28, 1986.
GOBATTO, G.E., TREZ, E.G., FARDO, R.G. Câncer de pele: análise de 435 casos.Rev CientAMECS, Caxias do Sul, v.5, n.2, p. 117-122, 1996.
GONÇALVES, M.P.P. et ai. Epidemiologia e tratamento do câncer de pele. Rev Med Minas Gerais, Belo Horizonte, v.6, n. I , p.8-11, 1996.
GUTIERREZ-STEIL, C. etal. Suniight induced basal cell carcinoma tumor cells and ultraviolet-B irradiated psoriatic plaques express Fas ligand (CD95L).J Clin Invest, Newyork, v. 01 , n. , p.33-39, 1998.
LEAR, J.T., SMITH, A.G. Basal celi carcinoma. Postgrad MedJ, London, v. 73, n. 863 , p.538-542, 1997.
LEAR, J.T. et al. A comparison of risk factors for malignant melanoma, squamous cell carcinoma and basal cell carcinoma in the UK. Int J Clin Pract,London, v.52, n.3, p. 145-149, 1998.
LEAR, J.T.et al. Risk factor for basal cell carcinoma in the UK: a case control study in 806 patients.JR SocMed,London, 1997.
MACHADO FILHO, C.A.S. et ai. Neoplasias malignas cutâneas: estudo epidemiológico. An Bras Dermatol, Rio de Janeiro, v. 71, n.6, p.479484, 1996.
MAIA, M., PROENÇA, N.G., MORAES, J.C. Risk factors for basal cell carcinoma: a case control study. Rev Saúde Públ, São Paulo, n.29, v. l , p.27-37, 1995.
MARKS, R. et al. The incidence ofnon-melanocytic skin cancer in Australian population: results ofa five years prospective study.Med JA ust, Sydney, v. 150, p.475-478, 1989.
MAURER, T.A. et al. Cutaneous squamous cell carcinoma in human immunodeficiencyvirus-infected patients. A study of epidemiologic risk factors, human papillomavirus, and p53 expression. Arch Dermatol, Chicago IL, v. 133, n.5, p.577-583, 1997.
MIGLIAVACCA, A. et al. Carcinoma basocelular: revisão de 381 casos no Hospital de Clínicas de Porto Alegre. Rev HCPA & Fac Med Univ Fed Rio Gd do Sul, Porto Alegre, v. 10, n.2, p.95-98, 1990.
NASSER, N. Incidência de câncer de pele em Blumenau, SC, 1980-1990.An Bras Dermatol, Rio de Janeiro, v.68, n.2, p. 77-78, 1993.
PRADO, H. Câncer de pele: Piauí, 1964-1984. 1. Carcinoma basocelular. An Bras Dermatol, Rio de Janeiro, v.62, n.3, p. 143-146, 1987.
QUINN, A.G. Ultrviolet radiation and skin carcinogenesis. Br J Hosp Med, London, v.58, n.6, p.261-264, 1997.
RAMOS-LUNA, L.A. et ai. Cancer de piei in el Hospital Universitario 1986-1990.DermatolRev Mex, v.38,n.4, p.253-259, 1994.
SANTOS, I.D.A.O. et al. Neoplasias malignas de pele. Anålise epidemiolögica de 1242 pacientes operados. JBM, Rio de Janeiro, v. 71 , n.2, p.61-68, 1998.
WALSH, D.S. Molecular genetics of skin cancer. Chicago IL, v. 13, p. 167-204, 1997.
YOUNG, S.R. et al. Basic principles of cancer genetics. JSC Med Assoc, Columbia SC, v.94, n. 7, p.299-305, 1998.
