Expectant versus active management with oxytocin for premature rupture of membranes at term
Keywords:
PROM, labor induced, pregnancy, high-risk, oxytocin, fetal membranes, premature ruptureAbstract
Objective
To compare tbe expectant and the active management with oxytocin for premature rupture ofmembranes at term.
Method
A multicentric randomized clinicai triai was carried out, evaluating variables concerning labor and delivery complications, and other maternal and neonatal outcomes. Two hundred pregnant women with premature rupture ofmembranes at term were selected from four public hospitais in the State ofSão Paulo, Brazil. They were randomly divided into two groups: active management, with oxytocin induction if labor had not initiated spontaneously within the first six hours after the rupture; and expectant management, waiting for the spontaneous onset of labor up to 24 hours. For the statistical analysis the Chi-square, Mann-Whitney, Fisher's Exact, Student's t tests were used.
Results
The values for the maio variables were not significantly different between the groups, although the negative outcomes were concentrated in the expectant management group. Only the latent period and the time between the rupture of the membranes and the delivery were significantly longer for the expectant management than for the active management with oxytocin stimulation.
Conclusion
Although the results did not show very important differences between the two managements for premature rupture of membraues at term, the active management bad a relatively better performance.
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References
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