OTOSCLEROSIS
Keywords:
otosclerosis, deafness, sodium fluoride, calcitoninAbstract
Otospongiosis is a bone dysplasia found only in the human temporal bone and consists of single ar multiple resorption areas followed by hea!ing with bone neoformation. The clinica/ result of the disease is conductive deafness when stirrup bane fixation occurs at the oval window ar neurosensory deafness when it affects the endosteum of the cochlea. Currently clinica/ treatment of otospongiosis is restricted to the use of sodium f/uoride (20mg) associated with ca/cium /actate to lessen the effects of this pathology. The fol/owing proposa/s for the clinicai handling of this condition have been made: cytokine inhibitors, salmon calcitonin and bisphosphonates. This brief review provides evidence of the etiopatho/ogy of otospongiosis and raises expectations for new therapeutic treatment.
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