IMPLANTS OF POLYCAPROLACTONE ANO NAFION® BLENDS IN TIBIA OF RATS
Keywords:
absorbable implants, biocompatible materiais, policaprolactone, ratsAbstract
Objective
Biodegradable and bioreabsorbable blends of polycaprolactone and NAFION® were tested as implant materiais. Polycaprolactone presents high crystallinity, which ensures a relative/y slow degradation process when it is implanted in biologica/ systems. The purpose of using NAFION® was the evaluation of the influence of an ionic conductive polymer on bane tissue ce/1 deposition rate therefore, bane defect repair.
Methods
ln vivo studies were carried out in rats with polycaprolactone/NAFION® blends containing 90% and 70% of polycaprolactone as materiais for bane defects repair.
Results
After 32 weeks, the formation of new bane inside of the implant of polycaprolactone!NAFION® 70/30 blends was observed, showing that these polymer blends act as a temporary support structure for bane regeneration. ln the implant of polycaprolactone/NAFION® 9017 O blends this behavior was not observed.
Conclusion
This blend composition of polycaprolactone/NAFION® 90/1O is not suitable to al/ow ce/1 growth.
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References
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