ACNE: A TREATMENT FOR EACH PATIENT
Keywords:
severe acne, adolescent, skin diseases, therapeuticsAbstract
Acne is a preva!ent disorder especial!y in adolescents and young adults. Severe acne is more common in male patients. Usua!/y, patients are initially seen by the clinicians or by the pediatricians. Severa/ therapeutic options are available from exfoliating products, topical and systemic antibiotic to systemic isotretinoin. A few factors must be considered when treating acne: clinica! presentation, severity and individual characteristics such as therapy adhesion and pregnancy. The goal of this paper is to clarify to the general practitioners the clinica! spectrum of acne and its treatment, taking into account cost and efficacy.
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References
Plewig G, Kligman AM. Acne and Rosácea. Berlin: Springer-Verlag; 2000.
Rivitti EA, Sampaio SAP. Dermatología. 2a. ed. São Paulo: Artes Médicas; 2000.
Strauss JS. Glândulas sebáceas. ln: Fitzpatrick TB, Eisen AZ, Wolff K, et ai. Dermatologia em medicina general. Buenos Aires: Panamericana; 1997. p.745-62.
FreedBerg IM, Eisen AZ, Wolf K, Austein KF, Goldsmith LA, Katz SL. Fitzpatrick's dermatology in general medicine. 5th ed. New York: McGraw-Hill; 1999.
Sá CMD. Acne: tratamento atualizado. São Paulo: EPUB; 2002.
Rasmussen JE. Diet and acne. Semin Dermatol. 1982; 6:766.
Leyden JJ. A review of the use of combination therapies for the treatment of acnes vulgaris. J Am Acad Dermatol. 2003; 49:S200-10.
Eady EA, Bojar RA, Jones CE, Cove JH, Holland KT, Cunliffe WJ. The effects of acne treatment with a combination of bezoyl peroxide and erythromycin on skin carriage of erythromycin-resistant propionibacteria. Br J Dermatol. 1996; 134(1):107-13.
Berson DS, Shalita AR. The treatment of acne: the role of combination therapies. J Am Acad Dermatol. 1995; 32(5 Pt 3):531-41
O.Thibout D. Acne. Semin Dermatol. 2002; 47:109-17.
Sykes NL, Webster GF. Acne. A review of optimum treatment. Drugs. 1994; 48(1):59-70.
Bergfeld WF. The evolving role of retinoids in the management of cutaneous conditions. Clinician. 1998; 16:1-32.
Chalker DK, Shalita A, Smith JG Jr, Swann RW. A double-blind study of the effectiveness of a 3% erythromycin and 5% benzoyl peroxide combination on the treatment of acne vulgaris. J Am Acad Dermatol. 1983; 9(6):933-6.
Weiss JS. Current options for the topical treatment of acne vulgaris. Pediatr Dermatol. 1997; 14(6):480-8
Webster GF. Topical tretinoin in topical therapy. J Am Acad Dermatol. 1998; 39(2 Pt 3):S38-44
Verschoore M, Poncet M, Czernielewski J, Sorba V, Clucas A. Adapalene 0,1% gel has low skin-irritation potencial. J Am Dermatol. 1997; 36(6 Pt 2):S104-9.
Cunliffe WJ, Poncet M, Loesche C, Verschoore M. A comparison of the efficacy and tolerability of adapaleno O,1% gel versus tretinoin 0,025% gel in pacients with acne vulgaris: a meta-anlysis of five randomized triais. Br J Dermatol. 1998; 139(Suppl 52):48-56.
Wolf JE Jr, Kaplan D, Kraus SJ, Loven KH, Rist T, Swinyer LJ, et ai. Eicacy and tolerability of combined topical treatment of acne vulgaris with adapaleno and clindamycin: a multicenter randomized study, investigator-blinded study. J Am Acad Dermatol. 2003; 49(3 Suppl):S211-7.
Kligman AM. The growing importance of topical retinoids in clinicai dermatology: a retrospective and prospective analysis. J Am Acad Dermatol. 1998; 39(2 Pt 3):S2-7.
Kenneth AA. Manual of dermatologic therapeutic. 5th ed. Boston: Spiral; 1995. p.9.
