DIAGNOSTIC ACCURACY OF THE CLINICAL FINDINGS IN KAWASAKI DISEASE
Keywords:
diagnosis, childhood, mucocutaneous lymph nade syndromeAbstract
Kawasaki disease is a systemic vasculitis of unknown etiology, more prevalent in children under 5 years and whose basically clinica/ diagnosis is made differentially, that is, ruling out other causes. lt is characterized by fever that lasts at least 5 days in addition to at least four other clinica/ signs: changes in the limbs, skin rashes, conjunctival injection without pus, changes in the lips and oral mucosae and cervical lymphadenopathy. Early diagnosis and immediate institution of therapy prevents serious sequelae, such as coronary aneurysm. This project intends to assess the accuracy of the main clinica/ signs/symptoms, one by one, for the diagnosis of this illness. Nane of them has shown satisfactory specificity or positive predictive value; the most common clinica/ signslsymptoms have better sensitivity and better negative predictive value. These resu/ts confirm the need for the diagnosis to be established by a set of clinica/ criteria until an adequate method is found, that is, one that has good accuracy when used atone.
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References
Burns JC, Glodé MP. Kawasaki Syndrome. Lancet. 2004; 364(9433):533-44.
Chung CJ, Stein L. Kawasaki disease: a review. Radiology. 1998; 208(1):25-33.
Melish ME, Hotez P. Síndrome de Kawasaki. ln: Gershon A, Hotez PJ. Krugman: doenças infecciosas na infância. 10a. ed. Rio de Janeiro: McGraw-Hill; 1998. p.183-91
Momenah T, Sanatani S, Potts J, Sandor GGS, Human DG, Patterson MWH. Kawasaki disease in the older child. Pediatrics. 1998; 102(1):e7.
Rowley HA, Shulman ST. Doença de Kawasaki. ln: Behrman RE, Kliegman RM, Jenson HB. Nelson tratado de pediatria. 17a. ed. Rio de Janeiro: Elsevier; 2005. p.718-20
Feigin RD, Cecchin FFF, Wissman SD. Kawasaki disease. ln: Oski's pediatrics principies & practice. 4th ed. Philadelphia: Lippinkott Williams & Wilkins; 2006. p.1015-20.
Bradley DJ, Glodé MP. Kawasaki disease: the mystery continues. West J Med. 1998; 168(1):23-9.
Brogan PA, Base A, Burgner D, Shingadia D, Tulloh R, Michie C, et ai. Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research. Arch Dis Childhood. 2002; 86: 286-90.
Freeman AF, Shulman ST. Kawasaki disease: summary of the American Heart Association Guideliness. Am Fam Physician. 2006; 74:1141-8, 1149-50.
O.Kawasaki T. Pediatric acute febrile mucocutaneous lymphnode syndrome with characteristic desquamation of fingers and toes: my clinicai observation of fifty cases. Pediatr lnfect Dis. 2002; 21(11):1-38.
Klevberg S, Farstad T, Perminow KV. lncidence of Kawasaki Disease. Tidsskr Nor Laegeforen. 2004; 124(13-14): 1774-5.
Morens DM, Melish ME. Kawasaki disease. ln: Feigin RD, Cherry JD. Textbook of pediatric diseases. 4th ed. Philadelphia: W.B. Saunders; 1998. v.1, p.995-1014
Sakane PT. Doença de Kawasaki. ln: Cossermelli W. Terapêutica em reumatologia. São Paulo: Lemos Editorial; 2000. p.669-73
Sakane PT, Marques HHS. Doença de Kawasaki. ln: Lopes AC. Tratado de clínica médica. São Paulo: Roca; 2006. v.3, p.3850-54.
Banfi Pacheco A. Enfermedad de Kawasaki. Rev Chil Pediatr. 2001; 72(6):487-95.
Anderson MS, Todd JK, Glodé MP. Delayed diagnosis of kawasaki syndrome: an analysis of the problem. Pediatrics. 2005; 115(4) e428-e133 (doi:10.1542/peds. 2004-1824).
Newburger JW, Fulton DR. Kawasaki disease. Curr Opin Pediatr. 2004; 16(5):508-14.
Helle R, Alsaker T, Norgârd G. Risk factors in Kawasaki's syndrome. Tidsskr Nor Laegeforen. 2004; 124(13-14):
-6.
Han RK, Sinclair B, Newman A, Silverman ED, Taylor GW, Walsh P, et ai. Recognition and management of Kawasaki disease. Can Med Assoe J. 2000; 162(6): 807-12.
Kushner HI, Burns JC, Bastian JF, Turner CH. The histories of Kawasaki disease. Prog Pediatric Cardiol. 2004; 19:91-7.
Meissner CH, Leung DYM. Kawasaki syndrome: where are the answers? Pediatrics. 2003; 112(3):672-6.
Sakane PT, Marques HHS. Doença de Kawasaki. ln: Fahrat CK, Carvalho ES, Carvalho LHFR. lnfectologia pediátrica. 2a. ed. Rio de Janeiro: Atheneu; 1999. p.663-6.
Cimaz R, Falcini F. An update on Kawasaki disease. Autoimmun Rev. 2003; 2(5):258-63.
Nasr 1, Tometzki AJ, Schofield OM. Kawasaki disease: an update. Clin Exp Dermatol. 2001; 26(1):6-12
Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et ai. Diagnosis, treatment, and long-term management of Kawasaki disease. Circulation. 2004; 110:2747-71.
Royle JB, Burgner D, Curtis N. The diagnosis and management of Kawasaki disease. J Pediatr Child Health. 2005; 41(3):87-93.
Singh S, Kansra S. Kawasaki disease. Natl Med J lndia. 2005; 18(1):20-4.
Porto Neto AC, Peixoto Filho AJ. Doença de Kawasaki: relato de caso e breve revisão. Rev AMRIGS. 1990; 34(2): 124-8.
Ruiz MM, Martín FIC, Andrés CB, Miguel MJG, Gómez MIJ, Cortés FM, et ai. lncidencia y características clinicas de la enfermedad de Kawasaki. An Pediatr. 2003; 59:323-7
Freeman AS, Shulman ST. lssues in the diagnosis of Kawasaki disease. Prog Pediatric Cardiol. 2004; 19: 123-8.
Ordoríez CP, Garcia Diaz R, Pierini AM. Enfermedad de Kawasaki. Arch Argent Dermatol. 1992; 42(4): 183-209.
Burgner D, Harnden A. Kawasaki disease: what is the epidemiology telling us about the etiology? lnt J lnfect Dis. 2005; 9(4):185-94.
Burns JC, Glodé MP. Kawasaki disease: a brief history. Pediatrics. 2000; 106(2):E27.
Amilachwari M, Rueda G, Kovalsky S, Barra V, Orta L, Pérez S. Enfermedad de Kawasaki: aspecto de laboratorio. Gac Méd Caracas. 1994; 102(3):205-8.
Gouveia C, Brito MJ, Ferreira GC, Ferreira M, Nunes MA, Machado MC. Kawasaki disease. Rev Porto Cardiol. 2005; 24(9):1093-113.
Falcini F. Kawasaki disease. Curr Opin Rheumatol. 2006; 18(1):33-8.
Chakrabartty S, Premanik S, Thapa R. Difficulties in the diagnosis of Kawasaki disease. lndian Pediatr. 2006; 43(8):728-31.
Asadi-Pooya AA, Borzoee M, Amoozgar H. The experience with 113 patients with Kawasaki disease in Fars Province, lran. Turk J Pediatr. 2006; 48(2): 109-14.
Rujiter FT, Wolfs TF, Geelen SP, Faber TE. Persistent fever of unknown origin in two infants caused by the atypical form of Kawasaki disease. Ned Tijdschr Geneeskd May. 2004; 148(18):892-5.
Magalhães CM, Mello MC. Relapse on Kawasaki disease, Brasil. J Pediatr. 1999; 75(3):204-6.