Chagas disease

Authors

  • Silvio Santos Carvalhal Professor Titular do Departamento de Clínica Médica e de Anatomia Patológica da Faculdade de Ciências Médicas da PUCCAMP

Keywords:

south american trypanosomiasis, Chagas cardiomyopathy

Abstract

The author believes that Trypanosoma cruzi is the only cause of Chagas disease. Howeper, in chronic stage, many patients do not show parasites in the diseased myocardium. According to this, the author accepts the the01Y that an autoimmune mechanism is destroying the myocardium cells. Furthermore, also in chronic cases, with pery scanty parasites and disproportionate amount of myocardium fibers destroyed, the author admits both, direct parasitic aggression and autoimmune mechanism, acting together in the same heart.

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References

ANDRADE, Z. Anatomia patológica da doença de chagas. Revista Goiana de Medicina, Goiânia, v.4, p.103-199, 1958.

CUNHA NETO, E. Imunopatogênese da cardiopatia chagásica crónica humana. São Paulo: [s.n.], 1994. Tese (Doutorado) Instituto de Ciências Biomédicas-USP.

HIGUCHI, M.L., BRITO, T. , REIS, M.M. Correlation between Trypanossoma cruzi parasitism and myocardial inflamatory infiltrate in human chronic chagasic myocarditis: light microscopy and immunohistochemical finding. Cardiovascular Pathology, v. 2, p. 101, 1993.

LARANJA, F.s., DIAS, E., _NÓBREGA, G., MIRANDA, A. Chagas disease. a clinical epidemiologic and pathologic study. Circulation, Dallas, v.14, p.1035-1060, 1956.

TEIXEIRA, A.R.L., TEIXEIRA, L.s., BUCH, C.A. The immunology of chagas disease: the production of lesions in rabbits similar to thosc of chronic chagas disease in man. American Journal of Pathology, Philadelphia, v.80, p. 163-177, 1975.

TEIXEIRA, V.P.A. A suprarenal e a forma crónica da doença de chagas. Uberaba : [s.n.], 19—. Tese (Doutorado) – Faculdade de Medicina do Triângulo Mineiro.

Published

1995-08-31

How to Cite

Santos Carvalhal, S. (1995). Chagas disease. Revista De Ciências Médicas, 4(2). Retrieved from https://seer.sis.puc-campinas.edu.br/cienciasmedicas/article/view/10739

Issue

Section

Artigos de Revisão