Alterações de parâmetros laboratoriais em pacientes com COVID-19
uma revisão sistemática
DOI:
https://doi.org/10.24220/2318-0897v31e2022a5379Palavras-chave:
Biomarcadores, Covid-19, Diagnóstico laboratorialResumo
O objetivo deste estudo foi identificar e reunir os principais achados disponíveis no começo da pandemia, acerca das alterações laboratoriais de pacientes internados com COVID-19 e discutir a predominância dessas alterações na gravidade do curso da doença. Trata-se de uma revisão sistemática de literatura, restringida a publicações até abril de 2020, utilizando as bases de dados Lilacs e Pubmed. Um total de 381 publicações foram encontradas nas bases de dados consultadas e destas, 17 publicações foram elegíveis para análise conforme os critérios de inclusão e exclusão. Parâmetros laboratoriais como a redução de linfócitos e elevação de D-dímeros, lactato desidrogenase e proteína C reativa parecem estar ligados à infecção pelo SARS-CoV-2 e podem servir como indicadores prognósticos da doença. A linfocitopenia e o aumento de D-dímeros são marcadores relacionados ao agravamento da doença e a desfechos desfavoráveis como óbito.
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