Atuação do nutricionista em neurociência nutricional
Palavras-chave:
Alimentação, Comportamento alimentar, Neurociências, Nutrição, PsiquiatriaResumo
Objetivo
Discutir temas atuais da inserção do nutricionista na área da Neurociência Nutricional, abordando conceitos, as principais áreas de investigação e suas potencialidades, além das lacunas que necessitam de mais foco.
Métodos
Trata-se de um ensaio teórico e reflexivo, no qual se buscou basear a discussão focando nos principais tópicos de pesquisa em Neurociência Nutricional: comportamento alimentar e sua influência na saúde humana; a relação da Nutrição e do estado nutricional com a memória e os transtornos de humor; aspectos nutricionais envolvidos nos transtornos do neurodesenvolvimento; nutrição no tratamento de doenças neurológicas e epilepsia. A discussão foi amparada por artigos científicos da área, diretrizes e protocolos clínicos fornecidos por agências especialistas em Alimentação e Nutrição e em cuidados médicos.
Resultados
O campo de investigação que estuda a relação entre as funções cerebrais e a alimentação e nutrição denominado Neurociência Nutricional tem por objetivo ampliar o entendimento sobre a relação entre aspectos do consumo alimentar, o aporte nutricional e a função cerebral, bem como suas implicações em processos considerados normais/homeostáticos e sua influência na saúde cerebral e em processos neurobiológicos e patológicos. Nesse artigo reflexivo, abordamos aspectos do comportamento alimentar, papel da nutrição em transtornos psiquiátricos e do neurodesenvolvimento, memória e doenças neurológicas, as áreas mais proeminentes e
promissoras no momento.
Conclusão
A Neurociência Nutricional vem se consolidando como uma área promissora para a atuação do nutricionista na pesquisa e na prática profissional. Fortalecer as bases curriculares de formação e treinamento do nutricionista, considerando as melhores evidências na área, é fundamental.
Referências
Rozin P. The meaning of food in our lives: a cross-cultural perspective on eating and well-being. J Nutr Educ Behav 2005;37. doi: https://doi.org/10.1016/S1499-4046(06)60209-1.
Zhou W, Zhao L, Mao Z, Wang Z, Zhang Z, Li M. Bidirectional communication between the brain and other organs: the role of extracellular vesicles. Cell Mol Neurobiol. 2023;43:2675-96. doi: https://doi.org/10.1007/S10571-023-01345-5.
Sarvottam K, Gajbhiye RN, Arvind A, Yadav BS. Crosstalk between brain and the peripheral tissues. Brain Organ Commun 2025:273–94. doi: https://doi.org/10.1016/B978-0-443-22268-9.00015-6.
Badaeva AV, Danilov AB, Clayton P, Moskalev AA, Karasev A V, Tarasevich AF, et al. Perspectives on neuronutrition in prevention and treatment of neurological disorders. Nutrients 2023;15. doi: https://doi.org/10.3390/NU15112505.
Topcuoglu, MA, Arsava E. Neuronutrition: an emerging concept. In: Arsava EM, editor. Nutrition in Neurologic Disorders. Cham: Springer; 2017. doi: https://doi.org/https://doi.org/10.1007/978-3-319-53171-7_10.
Devi A, Narayanan R. A review on neuronutrition. Asian J Dairy Food Res 2019;38:128-33. doi: https://doi.org/10.18805/ajdfr.DR-1454.
Matheus H, Fernandes A, Barbosa S, Barbosa GC, Thaís L, Souza R, et al. Influências da reforma psiquiátrica para a construção da neuronutrição no Brasil: uma revisão de literatura. Rev Eletr Acervo Saúde. 2022;15(4):1-8. doi: https://doi.org/https://doi.org/10.25248/reas.e10136.2022.
Marx W, Moseley G, Berk M, Jacka F. Nutritional psychiatry: the present state of the evidence. Proc Nutr Soc. 2017;76:427-36. doi: https://doi.org/10.1017/S0029665117002026.
Adan RAH, van der Beek EM, Buitelaar JK, Cryan JF, Hebebrand J, Higgs S, et al. Nutritional psychiatry: towards improving mental health by what you eat. Eur Neuropsychopharmacol. 2019;29:1321-32. doi: https://doi.org/10.1016/j.euroneuro.2019.10.011.
Kim JM. Ketogenic diet: old treatment, new beginning. Clin Neurophysiol Pract. 2017;2:161-2. doi: https://doi.org/10.1016/J.CNP.2017.07.001.
Höhn S, Dozières-Puyravel B, Auvin S. History of dietary treatment: Guelpa & Marie first report of intermittent fasting for epilepsy in 1911. Epilepsy Behav. 2019;94:277-80. doi: https://doi.org/10.1016/j.yebeh.2019.03.018.
Socała K, Doboszewska U, Szopa A, Serefko A, Włodarczyk M, Zielińska A, et al. The role of microbiotagut-brain axis in neuropsychiatric and neurological disorders. Pharmacol Res. 2021;172. doi: https://doi.org/10.1016/j.phrs.2021.105840.
Kachani A, Cordás T. Nutrição em Psiquiatria. 2nd ed. São Paulo: Manole; 2021.
Ximenes RCC. Transtornos Alimentares e Neurociência. Curitiba: Appris; 2019.
Craig AD. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol. 2003;13:500-5. doi: https://doi.org/10.1016/S0959-4388(03)00090-4.
Critchley HD, Garfinkel SN. Interoception and emotion. Curr Opin Psychol. 2017;17:7-14. doi: https://doi.org/10.1016/J.COPSYC.2017.04.020.
Campos A, Port JD, Acosta A. Integrative hedonic and homeostatic food intake regulation by the central nervous system: insights from neuroimaging. Brain Sci. 2022;12. doi: https://doi.org/10.3390/brainsci12040431.
Stover PJ, Field MS, Andermann ML, Bailey RL, Batterham RL, Cauffman E, et al. Neurobiology of eating behavior, nutrition, and health. J Intern Med. 2023;294:582-604. doi: https://doi.org/10.1111/joim.13699.
Sinha R. Role of addiction and stress neurobiology on food intake and obesity. Biol Psychol. 2018;131:5-13. doi: https://doi.org/10.1016/j.biopsycho.2017.05.001.
Berthoud HR, Münzberg H, Morrison CD. Blaming the brain for obesity: integration of hedonic and homeostatic mechanisms. Gastroenterology. 2017;152:1728-38. doi: https://doi.org/10.1053/J.GASTRO.2016.12.050.
Ministério do Desenvolvimento Social (Brasil). Princípios e Práticas para Educação Alimentar e Nutricional. Brasilia: MDS; 2018.
Alfaris N, Waldrop S, Johnson V, Boaventura B, Kendrick K, Stanford FC. GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review. eClinicalMedicine. 2024;75:102782. doi: https://doi.org/10.1016/J.ECLINM.2024.102782.
Rychescki GG, Santos GR, Bertin CF, Pacheco CN, Antunes LC, Stanford FC, et al. Online cognitivebehavioral therapy-based nutritional intervention via instagram for overweight and obesity. Nutrients. 2024;16:4045. doi: https://doi.org/10.3390/NU16234045.
Boaventura B, Stanford FC. Dietitians’ role in obesity care: insights from the Academy of Nutrition and Dietetics. Hepatobiliary Surg Nutr. 2025;14:159-62. doi: https://doi.org/10.21037/HBSN-2024-672.
Whitmer RA, Gunderson EP, Quesenberry CP, Zhou J, Yaffe K. Body mass index in midlife and risk of alzheimer disease and vascular dementia. Curr Alzheimer Res. 2007;4:103-9. doi: https://doi.org/10.2174/156720507780362047.
Albanese E, Launer LJ, Egger M, Prince MJ, Giannakopoulos P, Wolters FJ, et al. Body mass index in midlife and dementia: systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies. Diagnosis Assess Dis Monit. 2017;8(1):165-78. doi: https://doi.org/10.1016/J.DADM.2017.05.007.
Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kåreholt I, Winblad B, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol. 2005;62:1556-60. doi: https://doi.org/10.1001/ARCHNEUR.62.10.1556.
Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, et al. Defeating Alzheimer’s disease and other dementias: a priority for European science and society. Lancet Neurol. 2016;15:455-532. doi: https://doi.org/10.1016/S1474-4422(16)00062-4.
National Institute for Health and Care Excellence. Dementia, disability and frailty in later life – mid-life approaches to delay or prevent onset [Internet]. Manchester: Institute; 2015 [cited 2024 Nov 11]. Available from: https://www.nice.org.uk/guidance/ng16.
Kivim€ Aki M, Luukkonen R, David Batty G, Ferrie JE, Pentti J, Nyberg ST, et al. Body mass index and risk of dementia: analysis of individual-level data from 1.3 million individuals. Alzheimers Dement. 2018;14:601-9. doi: https://doi.org/10.1016/j.jalz.2017.09.016.
Spencer SJ, Korosi A, Layé S, Shukitt-Hale B, Barrientos RM. Food for thought: how nutrition impacts cognition and emotion. Npj Sci Food. 2017;1:1-8. doi: https://doi.org/10.1038/s41538-017-0008-y.
Wiles NJ, Northstone K, Emmett P, Lewis G. ‘Junk food’ diet and childhood behavioural problems: results from the ALSPAC cohort. Eur J Clin Nutr. 2007;63:491-8. doi: https://doi.org/10.1038/sj.ejcn.1602967.
Muñoz-García MI, Martínez-González MA, Martín-Moreno JM, Razquin C, Cervantes S, Guillén-Grima F, et al. Sugar-sweetened and artificially-sweetened beverages and changes in cognitive function in the SUN project. Nutr Neurosci. 2020;23:946-54. doi: https://doi.org/10.1080/1028415X.2019.1580919.
Kim JY, Kang SW. Relationships between dietary intake and cognitive function in healthy Korean children and adolescents. J Lifestyle Med. 2017;7:10-7. doi: https://doi.org/10.15280/JLM.2017.7.1.10.
Joffre C, Nadjar A, Lebbadi M, Calon F, Laye S. n-3 LCPUFA improves cognition: the young, the old and the sick. Prostaglandins Leukot Essent Fatty Acids. 2014;91(1):1-20. doi: https://doi.org/10.1016/J.PLEFA.2014.05.001.
Lamport DJ, Saunders C, Butler LT, Spencer JP. Fruits, vegetables, 100% juices, and cognitive function. Nutr Rev. 2014;72:774-89. doi: https://doi.org/10.1111/NURE.12149.
Muñoz-García MI, Martínez-González MA, Razquin C, Fernández-Matarrubia M, Guillén-Grima F, Toledo E. Exploratory dietary patterns and cognitive function in the “Seguimiento Universidad de Navarra” (SUN) Prospective Cohort. Eur J Clin Nutr. 2021;76:48-55. doi: https://doi.org/10.1038/s41430-021-00922-5.
Hallböök T, Ji S, Maudsley S, Martin B. The effects of the ketogenic diet on behavior and cognition. Epilepsy Res. 2012;100:304-9. doi: https://doi.org/10.1016/j.eplepsyres.2011.04.017.
Gomes Gonçalves N, Cacau LT, Ferreira NV, Lotufo PA, Goulart AC, Viana MC, et al. Adherence to the planetary health diet and cognitive decline: findings from the ELSA-Brasil study. Nat Aging. 2024;4:1465-76. doi: https://doi.org/10.1038/s43587-024-00666-4.
Archer E, Marlow ML, Lavie CJ. Controversy and debate: memory-based methods paper 1: the fatal flaws of food frequency questionnaires and other memory-based dietary assessment methods. J Clin Epidemiol. 2018;104:113-24. doi: https://doi.org/10.1016/J.JCLINEPI.2018.08.003.
Hebben N, Corkin S, Eichenbaum H, Shedlack K. Diminished ability to interpret and report internal states after bilateral medial temporal resection: case H.M. Behav Neurosci. 1985;99:1031-9. doi: https://doi.org/10.1037//0735-7044.99.6.1031.
Branchi I, Poggini S, Capuron L, Benedetti F, Poletti S, Tamouza R, et al. Brain-immune crosstalk in the treatment of major depressive disorder. Eur Neuropsychopharmacol. 2021;45:89-107. doi: https://doi.org/10.1016/J.EURONEURO.2020.11.016.
Ceolin G, Breda V, Koning E, Meyyappan AC, Gomes FA, Moreira JD, et al. A possible antidepressive effect of dietary interventions: emergent findings and research challenges. Curr Treat Options Psychiatry. 2022;9:151-62. doi: https://doi.org/10.1007/S40501-022-00259-1.
Liao Y, Xie B, Zhang H, He Q, Guo L, Subramaniapillai M, et al. Efficacy of omega-3 PUFAs in depression: a meta-analysis. Transl Psychiatry. 2019;9:2-9 doi: https://doi.org/10.1038/S41398-019-0515-5.
Ceolin G, Antunes LDC, Moretti M, Rieger DK, Moreira JD. Vitamin D and depression in older adults: lessons learned from observational and clinical studies. Nutr Res Rev. 2023;36:259-80. doi: https://doi.org/10.1017/S0954422422000026.
Gabriel FC, Oliveira M, Martella BDM, Berk M, Brietzke E, Jacka FN, et al. Nutrition and bipolar disorder: a systematic review. Nutr Neurosci. 2023;26:637-51. doi: https://doi.org/10.1080/1028415X.2022.2077031.
Zielińska M, Łuszczki E, Dereń K. Dietary nutrient deficiencies and risk of depression (Review Article 2018-2023). Nutrients. 2023;15:2433. doi: https://doi.org/10.3390/NU15112433.
Lai JS, Hiles S, Bisquera A, Hure AJ, McEvoy M, Attia J. A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults. Am J Clin Nutr. 2014;99:181-97. doi: https://doi.org/10.3945/AJCN.113.069880.
Matison AP, Mather KA, Flood VM, Reppermund S. Associations between nutrition and the incidence of depression in middle-aged and older adults: a systematic review and meta-analysis of prospective observational population-based studies. Ageing Res Rev. 2021;70. doi: https://doi.org/10.1016/J.ARR.2021.101403.
Riedinger MA, Mesbah R, Koenders M, Henderickx JGE, Smits WK, El Filali E, et al. A healthy dietary pattern is associated with microbiota diversity in recently diagnosed bipolar patients: the Bipolar Netherlands Cohort (BINCO) study. J Affect Disord. 2024;355:157-66. doi: https://doi.org/10.1016/J.JAD.2024.03.105.
Wu PY, Chen KM, Belcastro F. Dietary patterns and depression risk in older adults: systematic review and meta-analysis. Nutr Rev. 2021;79:976-87. doi: https://doi.org/10.1093/NUTRIT/NUAA118.
Jain R, Larsuphrom P, Degremont A, Latunde-Dada GO, Philippou E. Association between vegetarian and vegan diets and depression: a systematic review. Nutr Bull. 2022;47:27-49. doi: https://doi.org/10.1111/NBU.12540.
Gomes-da-Costa S, Fernandéz-Pérez I, Borras R, Lopez N, Rivas Y, Ruiz V, et al. Is a vegetarian diet beneficial for bipolar disorder? Relationship between dietary patterns, exercise and pharmacological treatments with metabolic syndrome and course of disease in bipolar disorder. Acta Psychiatr Scand. 2024;150:209-22. doi: https://doi.org/10.1111/ACPS.13733.
Firth J, Marx W, Dash S, Carney R, Teasdale SB, Solmi M, et al. The effects of dietary improvement on symptoms of depression and anxiety: a meta-analysis of randomized controlled trials. Psychosom Med. 2019;81:265-80. doi: https://doi.org/10.1097/PSY.0000000000000673.
Chrysafi M, Jacovides C, Papadopoulou SK, Psara E, Vorvolakos T, Antonopoulou M, et al. The potential effects of the ketogenic diet in the prevention and co-treatment of stress, anxiety, depression, schizophrenia, and bipolar disorder: from the basic research to the clinical practice. Nutrients. 2024;16(11):1546. doi: https://doi.org/10.3390/NU16111546.
Sánchez-Villegas A, Martínez-González MA, Estruch R, Salas-Salvadó J, Corella D, Covas MI, et al. Mediterranean dietary pattern and depression: the PREDIMED randomized trial. BMC Med. 2013;11:1-12. doi: https://doi.org/10.1186/1741-7015-11-208/TABLES/4.
Jacka FN, O’Neil A, Opie R, Itsiopoulos C, Cotton S, Mohebbi M, et al. A randomised controlled trial of dietary improvement for adults with major depression (the “SMILES” trial). BMC Med. 2017;15:1-13. doi: https://doi.org/10.1186/S12916-017-0791-Y/TABLES/2.
Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, et al. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: a randomized controlled trial (HELFIMED). Nutr Neurosci. 2019;22:474-87. doi: https://doi.org/10.1080/1028415X.2017.1411320.
Institute N for H and CE (NICE). Molloy A. Depression in adults: screening, treatment and management. Pharm J. 2022;30(7970). doi: https://doi.org/10.1211/pj.2023.1.175372.
Khachadourian V, Mahjani B, Sandin S, Kolevzon A, Buxbaum JD, Reichenberg A, et al. Comorbidities in autism spectrum disorder and their etiologies. Transl Psychiatry. 2023;13:1-7. doi: https://doi.org/10.1038/s41398-023-02374-w.
World Health Organization. CID-11 para Estatísticas de Mortalidade e de Morbidade [Internet]. Gneve: Organization; c2024 [cited 2024 Nov 11]. Available from: https://icd.who.int/browse/2024-01/mms/pt.
American Psychiatric Association. DSM-5: Manual diagnóstico e estatístico de transtornos mentais. 5th edição. Porto Alegre: Artmed; 2015.
Doernberg E, Hollander E. Neurodevelopmental Disorders (ASD and ADHD): DSM-5, ICD-10, and ICD-11. CNS Spectr. 2016;21:295-9. doi: https://doi.org/10.1017/S1092852916000262.
Doyle N. Neurodiversity at work: a biopsychosocial model and the impact on working adults. Br Med Bull. 2020;135:108-25. doi: https://doi.org/10.1093/bmb/ldaa021.
Yu Y, Huang J, Chen X, Fu J, Wang X, Pu L, et al. Efficacy and safety of diet therapies in children with autism spectrum disorder: a systematic literature Review and Meta-Analysis. Front Neurol. 2022;13:1-11. doi: https://doi.org/10.3389/fneur.2022.844117.
Siafis S, Çıray O, Wu H, Schneider-Thoma J, Bighelli I, Krause M, et al. Pharmacological and dietarysupplement treatments for autism spectrum disorder: a systematic review and network meta-analysis. Mol Autism 2022;13:1-17. doi: https://doi.org/10.1186/s13229-022-00488-4.
Lange KW, Lange KM, Nakamura Y, Reissmann A. Nutrition in the management of ADHD: a review of recent research. Curr Nutr Rep. 2023;12:383-94. doi: https://doi.org/10.1007/s13668-023-00487-8.
British Dietetic Association. Autism and diet [Internet]. Birmingham: Association; 2024 [cited 2024 Nov 11]. Available from: https://www.bda.uk.com/resource/autism-diet.html.
Marshall J, Ware R, Ziviani J, Hill RJ, Dodrill P. Efficacy of interventions to improve feeding difficulties in children with autism spectrum disorders: a systematic review and meta-analysis. Child Care Health Dev. 2015;41:278-302. doi: https://doi.org/10.1111/cch.12157.
Baraskewich J, von Ranson KM, McCrimmon A, McMorris CA. Feeding and eating problems in children and adolescents with autism: a scoping review. Autism. 2021;25:1505-19. doi: https://doi.org/10.1177/1362361321995631.
Molina-López J, Leiva-García B, Planells E, Planells P. Food selectivity, nutritional inadequacies, and mealtime behavioral problems in children with autism spectrum disorder compared to neurotypical children. Int J Eat Disord. 2021;54:2155-66. doi: https://doi.org/10.1002/eat.23631.
Esteban-Figuerola P, Canals J, Fernández-Cao JC, Arija Val V. Differences in food consumption and nutritional intake between children with autism spectrum disorders and typically developing children: a meta-analysis. Autism 2019;23:1079-95. doi: https://doi.org/10.1177/1362361318794179.
Fonseca NKO, Curtarelli VD, Bertoletti J, Azevedo K, Cardinal TM, Moreira JD, et al. Avoidant restrictive food intake disorder: recent advances in neurobiology and treatment. J Eat Disord. 2024;12:1-18. doi: https://doi.org/10.1186/S40337-024-01021-Z.
Esposito M, Mirizzi P, Fadda R, Pirollo C, Ricciardi O, Mazza M, et al. Food selectivity in children with autism: guidelines for assessment and clinical interventions. Int J Environ Res Public Health. 2023;20(6):5092. doi: https://doi.org/10.3390/ijerph20065092.
Lasheras I, Real-López M, Santabárbara J. Prevalence of gastrointestinal symptoms in autism spectrum disorder: a meta-analysis. An Pediatría. 2023;99:102-10. doi: https://doi.org/10.1016/j.anpede.2023.07.003.
Castro K, Faccioli LS, Baronio D, Gottfried C, Perry IS, Dos Santos Riesgo R. Effect of a ketogenic diet on autism spectrum disorder: a systematic review. Res Autism Spectr Disord. 2015;20:31-8. doi: https://doi.org/10.1016/j.rasd.2015.08.005.
Silva E, Hoffmann L, Castro K, Verly Junior E, Valle S, Vaz J. Nutrient intake variability and number of days needed to estimate usual intake in children and adolescents with autism spectrum disorder. Br J Nutr. 2025;133(5):1-24. doi: https://doi.org/10.1017/S0007114525000200.
Vasconcelos C, Perry IS, Gottfried C, Riesgo R, Castro K. Folic acid and autism: updated evidences. Nutr Neurosci. 2025;28(3):273-307. doi: https://doi.org/10.1080/1028415X.2024.2367855.
Castro K, Slongo Faccioli L, Baronio D, Gottfried C, Schweigert Perry I, Riesgo R. Body composition of patients with autism spectrum disorder through bioelectrical impedance. Nutr Hosp. 2017;34:875-9. doi: https://doi.org/10.20960/NH.210.
Castro K, Frye RE, Silva E, Vasconcelos C, Hoffmann L, Riesgo R, et al. Feeding-related early signs of autism spectrum disorder: a narrative review. J Pers Med 2024;14(8):823. doi: https://doi.org/10.3390/JPM14080823.
Salvat H, Mohammadi MN, Molavi P, Mostafavi SA, Rostami R, Salehinejad MA. Nutrient intake, dietary patterns, and anthropometric variables of children with ADHD in comparison to healthy controls: a casecontrol study. BMC Pediatr. 2022;22:1-9. doi: https://doi.org/10.1186/s12887-022-03123-6.
Jamshidnia A, Tavallaei M, Hosseinzadeh M. Food intake and attention-deficit/hyperactivity disorder in children: a case_control study. Clin Nutr ESPEN. 2021;44:342-7. doi: https://doi.org/10.1016/j.clnesp.2021.05.020.
Woo HD, Kim DW, Hong YS, Kim YM, Seo JH, Choe BM, et al. Dietary patterns in children with attention deficit/hyperactivity disorder (ADHD). Nutrients 2014;6:1539-53. https://doi.org/10.3390/nu6041539.
Park S, Cho SC, Hong YC, Oh SY, Kim JW, Shin MS, et al. Association between dietary behaviors and attention-deficit/hyperactivity disorder and learning disabilities in school-aged children. Psychiatry Res. 2012;198:468-76. doi: https://doi.org/10.1016/j.psychres.2012.02.012.
Lima S, Educação M. A Neuronutrição e seus benefícios em crianças com Transtorno do Déficit de Atenção com Hiperatividade (TDAH). Cad Pedagógico. 2024:21(13)1-29. doi: https://doi.org/10.54033/cadpedv21n13-046.
Lima WSJ, Lima WSJ, Silva JNSF, Silva Júnior MF, Silva ACVR, Araújo VTB. O papel da neuronutrição na prevenção dos sintomas do Transtorno do Déficit de Atenção e Hiperatividade (Tdah). REASE. 2022;8(8):1044-58. doi: https://doi.org/10.51891/rease.v8i8.6670.
Cerchiari A, Giordani C, Franceschetti S, Mazzafoglia S, Carosi F, Pizza F, et al. The Efficacy of the global intensive feeding therapy on feeding and swallowing abilities in children with Autism Spectrum Disorder: a pilot study. Children. 2023;10(7):1241. doi: https://doi.org/10.3390/CHILDREN10071241.
Lima De Oliveira P, Ramos Souza AP. Relato de Experiência Terapia com base em integração sensorial em um caso de Transtorno do Espectro Autista com seletividade alimentar. Cad Bras Ter Ocup. 2022;30:e2824. doi: https://doi.org/10.1590/2526-8910.ctoRE21372824.
Tsalamandris G, Hadjivassiliou M, Zis P. The Role of Nutrition in Neurological Disorders. Nutrients. 2023;15:4713. doi: https://doi.org/10.3390/NU15224713.
Volkert D, Beck AM, Faxén-Irving G, Frühwald T, Hooper L, Keller H, et al. ESPEN guideline on nutrition and hydration in dementia - Update 2024. Clin Nutr. 2024;43:1599-626. doi: https://doi.org/10.1016/J.CLNU.2024.04.039.
Burgos R, Bretón I, Cereda E, Desport JC, Dziewas R, Genton L, et al. ESPEN guideline clinical nutrition in neurology. Clin Nutr. 2018;37:354-96. doi: https://doi.org/10.1016/J.CLNU.2017.09.003.
Comissão Nacional de Incorporação de Tecnologias no Sitema Único de Saúde. Protocolo Clínico e Diretrizes Terapêuticas Doença de Parkinson. Brasília: CONITEC; 2017.
Ministério da Saúde (Brasil). Protocolo clínico e diretrizes terapêuticas da doença de Alzheimer. Brasília: Ministério 2024:33.
Lee H. The importance of nutrition in neurological disorders and nutrition assessment methods. Brain Neurorehabil. 2022;15:e1. doi: https://doi.org/10.12786/BN.2022.15.E1.
Lacerda ORM, Marques DKA, Souza IVB, Silva PE, Silva JM. Envelhecimento, neuronutrição e comportamento alimentar: abordando as doenças neurológicas na pessoa idosa. Soc Bras Cardiol. 2014;9:201-8.
Han X, Cai J, Li Y, Rong X, Li Y, He L, et al. Baseline Objective Malnutritional Indices as immune-nutritional predictors of long-term recurrence in patients with acute ischemic stroke. Nutrients. 2022;14,1337. doi: https://doi.org/10.3390/NU14071337.
Chen Y, Yang X, Zhu Y, Zhang X, Ni J, Li Y. Malnutrition defined by geriatric nutritional risk index predicts outcomes in severe stroke patients: a propensity score-matched analysis. Nutrients. 2022;14:4786. doi: https://doi.org/10.3390/NU14224786/S1.
Liampas A, Zis P, Hadjigeorgiou G, Vavougios GD. Selenium, stroke, and infection: a threefold relationship; where do we stand and where do we go? Nutrients. 2023;15:1405. doi: https://doi.org/10.3390/NU15061405.
Matsuyama H, Matsuura K, Ishikawa H, Hirata Y, Kato N, Niwa A, et al. Correlation between Serum Zinc Levels and Levodopa in Parkinson’s Disease. Nutrients 2021;13:4114. doi: https://doi.org/10.3390/NU13114114.
Haridas B, Kossoff EH. Dietary treatments for epilepsy. Neurol Clin. 2022;40:785-97. doi: https://doi.org/10.1016/J.NCL.2022.03.009.
Cervenka MC, Wood S, Bagary M, Balabanov A, Bercovici E, Brown MG, et al. International Recommendations for the management of adults treated with ketogenic diet therapies. Neurol Clin Pract. 2021;11:385-97. doi: https://doi.org/10.1212/CPJ.0000000000001007.
Neves GS, Lunardi MS, Lin K, Rieger DK, Ribeiro LC, Moreira JD. Ketogenic diet, seizure control, and cardiometabolic risk in adult patients with pharmacoresistant epilepsy: a review. Nutr Rev. 2021;79:931-44. doi: https://doi.org/10.1093/NUTRIT/NUAA112.
Tosefsky KN, Zhu J, Wang YN, Lam JST, Cammalleri A, Appel-Cresswell S. The role of diet in parkinson’s disease. J Parkinsons Dis. 2024;14:S21-34. doi: https://doi.org/10.3233/JPD-230264.
Al-kuraishy HM, Jabir MS, Albuhadily AK, Al-Gareeb AI, Jawad SF, Swelum AA, et al. Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: the guardian angle. Ageing Res Rev. 2024;95. doi: https://doi.org/10.1016/J.ARR.2024.102233.
Stanton AA. Specifically formulated ketogenic, low carbohydrate, and carnivore diets can prevent migraine: a perspective. Front Nutr. 2024;11. doi: https://doi.org/10.3389/FNUT.2024.1367570.
Ministério da Educação (Brasil). Diretrizes curriculares nacionais do curso de graduação em Nutrição. Brasília: MEC; 2024.
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2025 Júlia Dubois Moreira, Gilciane Ceolin, Letícia Carina Ribeiro, Luciana da Conceição Antunes, Débora Kurrle Riege
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
