Associação e comparação das alterações eletrocardiográficas de alto risco com os achados de lesão coronariana e o desfecho clínico intra-hospitalar em pacientes com Síndrome Coronariana Aguda
DOI:
https://doi.org/10.24220/2318-0897v30e2021a4836Palavras-chave:
Cateterismo cardíaco. Eletrocardiograma. Síndrome coronariana aguda.Resumo
Objetivo
Associar e comparar as citadas alterações do eletrocardiograma com lesões angiocoronarianas obstrutivas e com desfecho clínico.
Métodos
Estudo retrospectivo, observacional e transversal, com análise de prontuários eletrônicos de 165 pacientes internados com síndrome coronariana aguda e submetidos à cineangiocoronariografia, no período de abril de 2016 a março de 2017.
Resultados
Os padrões de alto risco estiveram presentes em 22 pacientes (13,3%). Houve mais lesões estenóticas graves (>70%) de artéria descendente anterior nos casos de achados eletrocardiográficos sem supradesnivelamento de ST (42,5%), com supradesnivelamento de ST (56,5%) e de alto risco (63,6%) em relação aos casos sem alterações típicas (11,1%; p=0,0002). Não houve diferença estatisticamente significante entre os desfechos clínicos de óbito (p=0,83) ou tempo de internação (p=0,28) entre nenhum grupo de padrão eletrocardiográfico. A análise de subgrupo também não mostrou diferença estatisticamente significante entre o tratamento instituído (clínico, endovascular ou cirúrgico) entre os casos de síndrome coronariana aguda com supradesnivelamento de ST, sem supradesnivelamento de ST ou de achados de alto risco (p>0,999).
Conclusão
Os padrões de alto risco estiveram associados a lesões coronarianas graves e evolução para tratamento invasivo (endovascular ou cirúrgico) de forma semelhante aos casos de infarto agudo do miocárdio com ou sem supradesnivelamento de segmento ST. Entretanto, não foi possível observar diferenças nos desfechos clínicos (tempo de internação e óbito) em nenhum dos grupos analisados.
Downloads
Referências
Thygesen K, Alpert JS, Jaffe AS. Fourth universal definition of myocardial infarction. ESC/ACC/AHA/WHF. Am Coll Cardiol. 2018;(138):618-51.
Chapman AR, Adamson PD, Mills NL. Assessment and classification of patients with myocardial injury and infarction in clinical practice. Heart. 2017;103(1):10-8. https://doi.org/10.1136/heartjnl-2016
Anand A, Shah ASV, Beshiri A, Jaffe AS, Mills NL. Global adoption of high-sensitivity cardiac troponins and the universal definition of myocardial infarction. Clin Chem. 2019;65(3):484-9. https://doi.org/10.1373/clinchem.2018.298059
Chapman AR, Lee KK, McAllister DA, Cullen L, Greenslade JH, Parsonage W, et al. Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome. Jama. 2018;319(11):11-68. https://doi.org/10.1056/NEJMc1913971
Birnbaum Y, Wilson JM, Fiol M, Luna AB, Eskola M, Nikus K. ECG diagnosis and classification of acute coronary syndromes. Ann Noninvasive Electrocardiol. 2014;19(1):4-14. https://doi.org/10.1111/anec.12130
Popov V, Yavisya A, Bulanova N, Ivanov G, Khamidova K, Panchenkova L, et al. Criteria for short and long-term prognosis in hospitalized patients based on the ecg signal characteristics at admission: rationale and study design. Georgian Med News. 2019;(295):84-9.
Hoh JM, U RB, Rajabali AN. Correlation of ECG findings with age, sex, co-morbid conditions and angiographic presentation among acute myocardial infarction patients in South India. J Ass Physicians India. 2019;67(11):22-4.
Pomozova TP, Lykov YV, Komarova IS, Dyatlov NV, Zhelnov VV. Clinical and laboratory features of primary acute myocardial infarction in patients with obstructive and non-obstructive coronary atherosclerosis. Kardiologiia. 2019;59(10S):41-51. https://doi.org/10.18087/cardio.2640
Nabati M, Emadi M, Mollaalipour M, Bagheri B, Nouraei M. ST-segment elevation in lead aVR in the setting of acute coronary syndrome. Acta Cardiol. 2016;71(1):47-54.
Misumida N, Kobayashi A, Fox JT, Hanon S, Schweitzer P, Kanei Y. Predictive value of ST-segment elevation in lead aVR for left main and/or three-vessel disease in Non-ST-segment elevation myocardial infarction. Ann Noninvasive Electrocardiol. 2016;21(1):91-7. https://doi.org/10.1111/anec.12272
Nakanishi N, Goto T, Ikeda T, Kasai A. Does T wave inversion in lead aVL predict mid-segment left anterior descending lesions in acute coronary syndrome? A retrospective study. Bri Med J Open. 2016;6(2):e010268. https://doi.org/10.1136/ bmjopen-2015-010268
Akhtar P, Rizvi SN, Tahir F, Saleem D, Mulla J, Saghir T. Angiocardiographic findings in patients with biphasic T-wave inversion in precordial leads. J Pak Med Assoc. 2012;62(6):548-51.
Birnbaum I, Birnbaum Y. High-risk ECG patterns in ACS: need for guideline revision. J Electrocardiol. 2013;46(6):535-9. https://doi.org/10.1016/j.jelectrocard.2013.06
Wegmann C, Pfister R, Scholz S, Markhof A, Wanke S, Kuhr K, et al. Diagnostic value of left bundle branch block in patients with acute myocardial infarction: a prospective analysis. Herz. 2015;40(8):1107-14. https://doi.org/10.1007/s00059-015-4326-z
Zhu T, Huitema A, Alemayehu M, Allegretti M, Chomicki C, Yadegari A, et al. Clinical presentation and outcome of patients with ST-segment elevation myocardial infarction without culprit angiographic lesions. Cardiovasc Revasc Med. 2015;16(4):217-20.
Lomakin NV, Buryachkovskaya LI, Sumarokov AB, Gerasimov AN, Gabbasov ZA. Acute coronary syndrome registry of high risk patients: 30-day outcome. Kardiologiia. 2019;59(11):14-20. https://doi.org/10.18087/cardio.2019.11.n723
Tang XF, Song Y, Xu JJ, Wang HH, Jiang L, Jiang P, et al. Clinical characteristics and prognosis between male and female patients with premature coronary artery disease after intervention. Zhonghua Xin Xue Guan Bing Za Zhi. 2019;47(10):798-805. https://doi/10.3760/cma.j.issn.0253-3758.2019.10.006
Piegas LS, Avezum A, Guimarães HP, Muniz AJ, Reis HJL, Santos ES, et al. Comportamento da síndrome coronariana aguda: resultados de um registro brasileiro. Arq Bras Cardiol. 2013;100(6):502-10. https://doi.org/10.5935/abc.20130101
Macias M, Peachey J, Mattu A, Brady WJ. The electrocardiogram in the ACS patient: high-risk electrocardiographic presentations lacking anatomically oriented ST-segment elevation: review. Am J Emerg Med. 2016;34(3):611-7. https:// doi.org/10.1016/j.ajem.2015.11. 047
Lipinski MJ, Mattu A, Brady WJ. Evolving electrocardiographic indications for emergent reperfusion: review. Cardiol Clin. 2018;36(1):13-26. https:/doi.org/10.1016/j.ccl.2017.08.002
Tamura A. Significance of lead aVR in acute coronary syndrome. World J Cardiol. 2014;6(7):630-7. https://doi.org/10.4330/wjc.v6.i7.630